Weave Bio has developed an AI-native platform to help research and discovery scientists get through the FDA regulatory submissions process 97% faster!
- Senior Backend Engineer (python/django)
- Staff Backend Engineer (python/django)
- Senior Customer Success Manager (B2B SaaS)
- Director of Sales (player-coach for 4+ Account Executives)
Please apply here: https://job-boards.greenhouse.io/weave
San Francisco (SF), Hybrid/Onsite 3 days/week (Tues/Wed/Thurs)
We work with robots that run biology experiments. The robots are accurate, but programming them by hand takes so long that most labs don't bother. So we wrote a compiler and visual editor a scientist can use. They describe their protocol in plain language, we parse it into a structured format, and compile that to optimized code. Our end goal is to build the infrastructure for autonomous science and a centralized cloud lab. Short demo: https://tinyurl.com/mrx63phb
The team is three software engineers, an automation engineer, the founders, and soon a designer. The codebase is one monorepo containing an OCaml compiler, Python backend services, and a TypeScript/React editor. The challenges come in the form of eliciting scientific context and tacit knowledge and in the fact that a protocol has to deterministically run correctly.
We are looking for at least 3 years of experience. OCaml isn't a requirement, just a willingness to learn it. Nice if you've done DSLs, compilers, life sciences or lab automation, an ML-family language, or LLM parsing and evals.
Apply: https://jobs.ashbyhq.com/tetsuwan/ad583fec-dc0a-4b6c-8171-41...
Otherling is a fashion e-commerce startup helping consumers discover emerging luxury brands. We're hiring a Senior Full-Stack Engineer to design, build, and maintain our platform end-to-end.
REQUIREMENTS - 4+ years in software development (CS degree or equivalent) - React, Next.js, Tailwind CSS - Python or Node.js - SQL/NoSQL/Postgres and data modeling - REST and/or GraphQL APIs - Docker and AWS (ECS, Cognito, S3, Lambda, RDS) - Shopify platform and API development - Plus: startup or luxury-fashion interest
APPLY Email otherling@vornoy.com, subject 'Otherling dev'. Include your resume and location (New York or Los Angeles).
I'm a founding engineer at MindFort (https://www.mindfort.ai). We build autonomous AI security agents that pen test your software before attackers do: finding, exploiting, and patching vulnerabilities. Backed by YC, Soma Capital, etc.
- Software Engineer (Backend + AI) | $150k–$250k + Equity: Architect and scale our agent systems from scratch. Python, Postgres, Docker, K8s, LangChain/LangGraph. Cybersecurity background a plus but not needed.
- AI Researcher | $150k–$250k + equity: Own the research behind how our agents reason, plan, and chain exploits. LLM fine-tuning, RL, eval design, multi-agent systems. Security or red-teaming background a plus.
Both roles include founding-level equity, 100% health coverage and unlimited PTO.
More Info + Apply At: https://www.ycombinator.com/companies/mindfort
Puntt AI is the system of record for enterprise marketing compliance. Our AI agents turn hours of manual brand and packaging review into minutes of automated precision. Danone, Nestlé, and Kenvue are live customers. The product works. Now we scale.
Forward Deployed Engineer | $190k + equity https://wellfound.com/l/2CiVyv
The FDE is the person in the room when an enterprise customer shows you their actual broken process. You run discovery, figure out what's really going wrong, configure and ship against it, and bring that signal back to product in a way the team can actually use. You work directly alongside our CEO in live enterprise cycles. What you learn shapes what we build next.
Best fit: solutions engineering, field engineering, or technical founder background. You've been in enterprise rooms, you get to the real problem fast, and you can build the thing that proves the fix. Full stack, AI-native, 7+ years.
Senior Applied AI Engineer | $185k-$210k + 0.75%-1.25% equity https://wellfound.com/l/2C3WzL
This role owns the agentic core -- multi-agent orchestration, RAG and retrieval, stateful async workflows (Temporal), and the eval frameworks that make compliance AI trustworthy at scale. If you've spent real time thinking about failure modes, observability, and what reliable actually means when LLMs are in the loop, that's who we're looking for.
5-7+ years production engineering. 1-2+ years building with LLMs in real applications. Strong Python. Hands-on RAG.
Opaxa is the AI agent platform that runs restaurant back-office operations. Not another dashboard — agents that take the work off the operator's plate and act: build the schedule and push it to action, place the order with distributors, audit the invoice for overcharges, draft the review reply. The operator approves what matters; the rest gets done.
The unfair part: the founder owns and runs a 40-location restaurant company with over 750 employee's — so Opaxa's first customer is a real, operating restaurant group with real data and real stakes from day one. Deep domain expertise is built in, and your work runs in real restaurants immediately, not after a six-month hunt for a design partner. Well-funded.
A working prototype is already built. Now I'm hiring a founding full-stack engineer to take it from prototype to production: own the architecture, the agent runtime, the backend, and the integrations the agents act through (Toast, Paycom, Sysco, and more), set the technical bar, and grow the team behind you.
You'd work directly with me — I own product, customers, and the domain; you own the AI and the build. We'd be hiring additional engineers and account managers within the first year.
You're a fit if you: - have shipped agentic systems to production — plan-and-act, not chatbots or wrappers - are a strong full-stack builder (Python and/or Node, Postgres, real infra) - use the latest AI tooling (Claude Code / Cursor) as your default want to own a whole product as the first engineer, and eventually lead
Stack: React/TypeScript, Python/Node, Postgres, the Anthropic API, integrations across the restaurant stack.
To apply: email me at colton@opaxa.ai with the most impressive agentic system you've personally shipped — what it did, what you owned, and what made it hard — plus your resume or links. I read every one and reply. Please write it yourself; if it's clearly AI-generated, I'll pass.
At Factory we build Droids, autonomous software development agents that review PRs, implement features, run tests, fix incidents, and handle migrations for enterprise engineering teams. Droid is model agnostic and surface agnostic, and works across your CLI, IDE, Web/Desktop app, CI/CD, Slack, and Linear. Customers include Nvidia, Adobe, Adyen, Klarna, and Ernst & Young.
We raised a $150M Series C at a $1.5B valuation, backed by Khosla Ventures, Sequoia, Blackstone, Insight Partners, NEA, and NVIDIA.
We're hiring across the stack:
- AI Engineer: agentic systems, LLM integrations, evals
- Fullstack Engineer: platform, APIs, auth, billing, terminal UIs
- Frontend Engineer: web and desktop apps (React, TypeScript, Electron)
- Platform Engineer: infrastructure, sandboxing, CI/CD, cloud
- Product Engineer: end-to-end feature ownership
- Data Engineer: pipelines, analytics, telemetry at scale
- Security Engineer / Research Engineer
Stack: TypeScript, React, Node.js/Bun, Python, GCP/AWS, Firestore, Electron.
We're also hiring in these roles: Enterprise & Mid-Market AEs, Solutions Engineers, Forward Deployed Engineers, Product Marketing, Product Manager, Product Designer, Partnerships, and Operations (RevOps, BizOps, People Ops, Recruiting). Some roles available in NYC and London.
In-office 5 days a week in SF (walking distance to Caltrain). Catered lunch and dinner, full medical/dental/vision, 401(k).
If you have strong opinions about how AI should actually work for production engineering systems at enterprise scale: we want to talk.
Apply: https://factory.ai/careers
https://jobs.gem.com/piqenergy/am9icG9zdDqgTj8NyVDwal1rIjQFn... for remote US, https://jobs.gem.com/piqenergy/am9icG9zdDqkYrMOHiz76MhEvW9nt... for San Francisco
Piq Energy builds software that helps renewable and large-load developers get projects connected to the electric grid faster. We automate grid interconnection studies and planning workflows.
You’ll own features end-to-end: interactive frontend, backend APIs, data pipelines, AI agents, and power systems simulation workflows. We’re looking for experienced generalists who like ownership, real-world impact, and scaling startups.
Stack: Typescript, Svelte, GraphQL, Mapbox, D3.js, Python, LLM agents, Postgres, workflow orchestration
Modal builds the serverless cloud used by many of the most popular AI companies you've heard of. People use Modal for inference, training, batch operations and also, sandboxes. A good example is the Ramp Inspect tool, that was built on Modal sandboxes. https://engineering.ramp.com/post/why-we-built-our-backgroun... — We also recently passed over a billion sandboxes created and on our way to 2B soon.
I am one of the hiring managers here, hiring for the Product Engineering team that builds the observability tooling for our developers. Modal is the cloud for many of our customers and we help them reason about what's happening in their systems, help them expand their use and generally have a good experience.
If you are interested in a product engineering role, please feel free to reach out directly via email at can@modal.com with a recent resume. This role is NYC or SF based and is on-site, so please mention your current location to be considered. I am especially looking for folks with deep ClickHouse, Postgres, Redis, and Python experience.
Please mention how you have used Modal or similar tools in the past and link to a recent resume. Resumes and emails that are clearly human-written will go to the front of the line. I wrote this by hand, so can you. Or can you?
Product Engineering Role: https://jobs.ashbyhq.com/modal/a4b8b2b6-5d0c-4ba6-9256-b84be...
For all other roles, please apply from our website.
All roles: https://modal.jobs
DataSF is looking for a Senior Data Engineer to help us build out the city's central Snowflake platform, which will ultimately power the majority of SF's analytics, open data, and ML efforts. This role is a mix of data infrastructure (CI/CD, terraform), building pipelines (ADF, dbt, Python), and platform eng and admin (Snowflake). See the position description for more info.
We're looking for folks with:
- Strong SQL and Python skills
- Deep data modeling experience
- Data infrastructure and devops experience (terraform, Actions)
- dbt and Snowflake experience are a big plus
- Know their way around a terminal
Apply here: https://careers.sf.gov/role/?id=3743990013401756
AI data centers are creating a massive new wave of electricity demand, and the grid is already stretched. Strobe is building an autonomous power company to help meet that demand: software that turns buildings, batteries, EVs, and generators into a distributed power plant that can buy, sell, and dispatch electricity in real time.
We’re a 6-person, well-funded team backed by top investors. This is early, high-ownership, and very real-world: the software you build will control physical assets and move money in energy markets. We are the only company actively trading distributed power in New York - the space is entirely new and unlocked by recent FERC regulation.
I’m looking for a staff engineer to own the data integrations and cloud infrastructure that make the whole system work. That means connecting to utilities, grid operators, OEM hardware, weather providers, and our optimization engine — then making sure it all runs reliably when market events are happening and dollars are on the line.
You’d work on things like:
* Wholesale market integrations with NYISO, CAISO, ERCOT: pricing, capacity markets, dispatch signals * OEM hardware integrations for monitoring, control, and telemetry * Utility data pipelines, including Green Button Connect / ESPI, interval usage, billing, and meter data from utilities like ConEd, PG&E, and SCE * Weather forecast pipelines feeding our scheduling engine * Event-driven AWS infrastructure using Lambda, API Gateway, AppSync/GraphQL, EventBridge, IoT Core, Timestream, Amplify, and CloudWatch * Terraform IaC, observability, alerting, and the reliability work needed when downtime has real financial consequences
Good fit if you have deep AWS experience, have used Terraform seriously in production, and write a lot of Python. Energy experience is a plus, but not required. Experience with utilities, government APIs, OEMs, hardware, telemetry, or other “real world is messy” systems is very relevant.
Stack: Python, TypeScript, Rust, Terraform, AWS, GraphQL/AppSync, MQTT, Grafana. We use an AI-agent-optimized monorepo and are investing heavily in agent-enabled engineering efficiency.
Small team, no layers, high trust.
Apply: keeley@strobepower.com or https://strobepower.com/careers. Please mention Hacker News.
We're building payment rails for AI agents; fully-owned rails across traditional banking and stablecoins, and the full set of funds flows that AI agents need to transact in the real world with businesses, consumers, and other agents (wallets, pay, request, credit, billing, and more).
We've raised from some of the most well-known operators in fintech & payments to shape how agents interact with the economy, from scratch.
https://natural.co if you'd like to learn more - email krish@natural.co if interested!
Axle Health builds scheduling and workforce management software to empower in-home healthcare providers to deliver exceptional, personalized care right where patients feel most comfortable—at home.
Hiring: hands on builders who thrive on in person collaboration. Ideal Senior SWE candidates have 8+ years of experience working with complex mission critical platforms.
We melted GPUs chasing Causal AI — now we run one of the world's fastest private supercomputers, the only non-Fortune 500 company on earth operating one. Patented causal math, proving what actually drives revenue for the world's best enterprises.
Hiring: SREs to run our supercomputer, C++ engineers for AI systems, data engineers for enterprise-scale pipelines, and backend Python engineers for the platform.
Customers: NVIDIA, Delta, Mars. $145M Series B. Hiring SREs, C++ AI, data, and backend Python engineers.
We build developer infrastructure for Physical AI. Robotics and embodied-AI teams run their data flywheel on us: visualization, multimodal logging (MCAP), search and curation, observability, eval, and fleet management. Stack is Rust on the backend and data side, TypeScript with WebGL and WASM for visualization, Python for ML and eval.
Series B, ~80 people, backed by Bessemer, founded by Cruise and Coinbase alumni. AV or robotics experience is a plus, not a requirement.
Open roles (Senior/Staff):
- ML Engineer
- Product Manager, Data + ML
- FDE, Europe
- Design Engineer
- Account Executive (Defense and Aerospace)
All roles and apply: https://www.foxglove.dev/careers
Questions: email in profile (mention HN)
We're building the operating system for the digital infrastructure of government. Authorium is a GovTech SaaS platform that unifies the messy, high-stakes workflows (procurement, grants, budgeting) that keep state and local governments running. We replace fragmented docs, spreadsheets and decades-old legacy systems with a unified data layer managing billions in public funds. Customers include California's CDSS, CalPERS, and EDD, plus major agencies in NY, Florida and Washington.
We're >40 people, growing 45% YoY, with a clear path to profitability in 2026. Real product-market fit, scale, and impact.
We're standing up our SF office as the war room for our hardest problems: modularizing our core domain, designing the next-gen workflow engine, building versioning and approval systems that hold up across dozens of customer configurations. You'd whiteboard, debug, and ship in person alongside a high-caliber team.
Stack: Ruby on Rails BE, Hotwire and Next.js FE, enterprise form and document capabilities. We're leveraging AI in our development process: Claude Code for specs, agentic testing, automated reviews.
Two roles open:
- Full-Stack Engineer (3+ yrs) | $148,750-$201,250 + equity | https://jobs.ashbyhq.com/Authorium/b59ff28c-3e3c-4190-abaa-a... - Senior Full-Stack Engineer (6+ yrs) | $170,000-$230,000 + equity | https://jobs.ashbyhq.com/Authorium/dc83e0dd-9279-4381-9930-f...
Both value deep fundamentals (system design, database optimization, clean architecture) over specific syntax. Bonus for Rails, document-heavy systems, or regulated-industry experience (GovTech, FinTech, HealthTech).
Benefits: 100% employee coverage, 401(k), flexible PTO, home office + commuter stipend.
Apply at the links above (mention Hacker News). I'm Jay, co-founder and xCIO of City of SF. Happy to connect directly if you have questions, just reply here or reach out jay@authorium.com